Deeper Tissue Imaging with Total Detection

Live imaging looks deeper

Iodixanol provides an easy and affordable solution to a problem that has limited resolution and brightness when imaging living samples.

Total internal reflection: a deeper look.

In the present paper, we have presented a Maxwellian boundary-type solution for total internal reflection with unbounded incident waves at an interface between two nonabsorbing media, in which the instantaneous, time varying, and time averaged radiant fluxes have been determined at all points in the two media. Solutions for the s and p polarizations were found for which the instantaneous tangen...

Digging deeper with CT imaging: slice-by-micro slice...

Saliency Detection with a Deeper Investigation of Light Field

Although the light field has been recently recognized helpful in saliency detection, it is not comprehensively explored yet. In this work, we propose a new saliency detection model with light field data. The idea behind the proposed model originates from the following observations. (1) People can distinguish regions at different depth levels via adjusting the focus of eyes. Similarly, a light f...

Optimization of Optical Excitation of Upconversion Nanoparticles for Rapid Microscopy and Deeper Tissue Imaging with Higher Quantum Yield

Relatively low quantum yield (QY), time-consuming scanning and strong absorption of light in tissue are some of the issues present in the development of upconversion nanoparticles (UCNPs) for biomedical applications. In this paper we systematically optimize several aspects of optical excitation of UCNPs to improve their applicability in bioimaging and biotherapy. A novel multi-photon evanescent...